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• New Evidence Links Calcium Channel Blockers to Increased Risk of ... - Medpage Today

  Tuesday, June 13, 2023

  Use of calcium channel blockers (CCBs), particularly cardioselective agents, had a modest but statistically significant association with glaucoma, a large meta-analysis showed.Overall, patients with a history of CCB treatment had a 23% higher likelihood of developing glaucoma as compared with individuals who never used the antihypertensives. The likelihood almost doubled among patients who received single-agent cardioselective CCBs. In contrast, beta-blocker therapy was associated with modestly reduced intraocular pressure (IOP), which is associated with a reduced risk of glaucoma.A number of other commonly used medications had no clear associations with glaucoma or IOP, including lipid-lowering drugs, antidepressants, and diabetes medications, reported ...
• Hydroxychloroquine is neutral on incidental cataracts in patients ... - Nature.com

  Wednesday, April 05, 2023

  To the best of our knowledge, this study is the first to investigate the correlation between the risks of cataracts and HCQ therapy. The statistical analysis showed that HCQ therapy did not increase the risk of cataracts in RA patients. The RA patients used in this study were selected from the NHIRD, which records the clinical information of approximately 99% of Taiwanese residents. With adjustments to remove confounders, the statistical analysis supported the hypothesis that there was no relationship between HCQ therapy and the risks of cataracts.RA is a common autoimmune inflammatory disease that can affect other organs throughout the ...